1.

Wang YH, Fu CL, Chen LB, Zhang CY, Chen JS, Zhang QM, Liang Y, Yang RL, Li Y, Zhang YN, Han YN, Yuan ZL, Chen YN, Li H, Pan Y, Hu S, Li M, Cao LP, Yao J. Microglia contribute to bipolar depression through Serinc2-dependent phospholipid synthesis. Proc Natl Acad Sci U S A. 2025 Sep 8;122(37):e2500116122. doi: 10.1073/pnas.2500116122.

2.

Liu YN, Wang QW, She XY, Li LJ, Wang B, Yang R, Li Q, Lu SY, Wang YH, Shen W, Fu CL, Li D, Yi L, Wang CX, Shi W, Cheng X, Cao L, Mi S, Yao J. A pancreas–hippocampus feedback mechanism regulates circadian changes in depression-related behaviors. Nature Neuroscience. 2025 Aug 11. doi: 10.1038/s41593-025-02040-y

3.

Zhang QM, Chen YF, Xing YY, Yang M, Li N, Jiang X, Gao H, Lu SY, Yao J. Anterior insular cortex regulates depression-like and ASD-like behaviors via the differential contribution of two subsets of microglia. Molecular Psychiatry. 2025 Aug 6; doi: /10.1038/s41380-025-03139-1

4.

Weng KK, Li WJ, Cheng XY, Xing YY, Fu X, Wang YH, Wang HC, Tian XL, Wang YQ, Li LZ, Yao J, Sheng X, Li JH, Zhang H. Metal–Organic Frameworks Modified Organic Bulk Heterojunction Interfaces for Effective Nongenetic Neuromodulation. ACS Nano. 2025 Apr 25;19(17): 16813-16828. doi:10.1021/acsnano.5c01516

5.

Liu YN, Wang QW, Lu SY, Shen W, Guo C, Xing Z, Li C, Sun S, Sui SF, Mi S, Gage F H, Yao J. Synaptotagmin-7 deficit causes insulin hypoactivity and contributes to behavioral alterations in mice. iScience. 2025 Apr 4;28(5):112354. doi: 10.1016/j.isci.2025.112354.

6.

Cheng XY, Li WJ, Wang YH, Weng KK, Xing YY, Huang YX, Sheng X, Yao J, Zhang H, Li JH. Highly Branched Au Superparticles as Efficient Photothermal Transducers for Optical Neuromodulation. ACS Nano. 2024 Oct 14;18(43): 29572-29584. doi: 10.1021/acsnano.4c07163

7.

Fu CL, Jiang X, Dong BC, Li D, She XY, Yao J. Protocol for transplantation of cells derived from human midbrain organoids into a Parkinson's disease mouse model to restore motor function. STAR Protoc. 2024 Sep 20;5(3):103251. doi: 10.1016/j.xpro.2024.103251.

8.

Tu YF, Qin J, Zhang QM, Tang TS, Wang LF, Yao J. Secretagogin regulates asynchronous and spontaneous glutamate release in hippocampal neurons through interaction with Doc2α. Life Medicine. 2024 Nov 14;2(5):lnad041. doi: 10.1093/lifemedi/lnad041.

9.

Wang QW, Qin J, Chen YF, Tu Y, Xing YY, Wang Y, Yang LY, Lu SY, Geng L, Shi W, Yang Y, Yao J. 16p11.2 CNV gene Doc2α functions in neurodevelopment and social behaviors through interaction with Secretagogin. Cell Rep. 2023 Jul 25;42(7):112691. doi: 10.1016/j.celrep.2023.112691.

10.

Wang QW, Wang YH, Wang B, Chen Y, Lu SY, Yao J. Synaptotagmin-7-mediated activation of spontaneous NMDAR currents is disrupted in bipolar disorder susceptibility variants. PLoS Biol. 2021 Jul 6;19(7):e3001323. doi: 10.1371/journal.pbio.3001323.

11.

Lu SY, Fu CL, Liang L, Yang B, Shen W, Wang QW, Chen Y, Chen YF, Liu YN, Zhu L, Zhao J, Shi W, Mi S, Yao J. miR-218-2 regulates cognitive functions in the hippocampus through complement component 3-dependent modulation of synaptic vesicle release. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2021770118. doi: 10.1073/pnas.2021770118.

12.

Chen Y, Wang YH, Zheng Y, Li M, Wang B, Wang QW, Fu CL, Liu YN, Li X, Yao J. Synaptotagmin-1 interacts with PI(4,5)P2 to initiate synaptic vesicle docking in hippocampal neurons.Cell Rep. 2021 Mar 16;34(11):108842. doi: 10.1016/j.celrep.2021.108842.

13.

Wang QW, Lu SY, Liu YN, Chen Y, Wei H, Shen W, Chen YF, Fu CL, Wang YH, Dai A, Huang X, Gage FH, Xu Q, Yao J. Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31438-31447. doi: 10.1073/pnas.2016416117. Epub 2020 Nov 23.

14.

Shen W, Wang QW, Liu YN, Marchetto MC, Linker S, Lu SY, Chen Y, Liu C, Guo C, Xing Z, Shi W, Kelsoe JR, Alda M, Wang H, Zhong Y, Sui SF, Zhao M, Yang Y, Mi S, Cao L, Gage FH, Yao J. Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4392-4399. doi: 10.1073/pnas.1918165117. Epub 2020 Feb 10.

15.

Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, Yao J. CRISPR interference-based specific and efficient gene inactivation in the brain. Nat Neurosci. 2018 Mar;21(3):447-454. doi: 10.1038/s41593-018-0077-5. Epub 2018 Feb 5. Erratum in: Nat Neurosci. 2018 Mar 15.

16.

Liu YN, Lu SY, Yao J. Application of induced pluripotent stem cells to understand neurobiological basis of bipolar disorder and schizophrenia.Psychiatry Clin Neurosci. 2017 Sep;71(9):579-599. doi: 10.1111/pcn.12528. Epub 2017 May 2.

17.

Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames TJ, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, PBDS, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J. Differential Responses to Lithium in Hyperexcitable Neurons from Bipolar Patients. Nature. 2015 Nov 5;527(7576):95-9. doi: 10.1038/nature15526. Epub 2015 Oct 28.

18.

Yu DX, Di Giorgio DP, Yao J, Marchetto MC, Brennand K, Wright R, Mei A, McHenry L, Lisuk D, Grasmik J, Silberman P, Silberman G, Jappelli R, Gage FH (2014). Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem Cell Reports. 2014 Feb 27;2(3):295-310. doi: 10.1016/j.stemcr.2014.01.009. eCollection 2014 Mar 11.

19.

Yao J, Kwon SE, Gaffaney JD, Dunning FM, Chapman ER (2012). Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles. Nature Neuroscience. 15(2): 243-249.

20.

Yao J, Gaffaney JD, Kwon SE, Chapman ER (2011). Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release. Cell. 147(3):666-77.

21.

Yao J, Mu Y, Gage FH (2012). Neural stem cells: mechanisms and modeling. Protein & Cell. 3(4): 251-261. (Review)

22.

Wu Y, Gu Y, Morphew MK, Yao J, Yeh FL, Dong M, Chapman ER (2012). All three components of the neuronal SNARE complex contribute to secretory vesicle docking in PC12 cells. Journal of Cell Biology. 198(3):323-30. 

23.

Yeh FL, Dong M, Yao J, Tepp WH, Lin G, Johnson EA, Chapman ER (2010). SV2 mediates entry of tetanus neurotoxin into central neurons. PLoS Pathogens. 6(11): e1001207.

24.

Yuan X, Yao J, Norris D, Tran DD, Bram RJ, Chen G, Luscher B (2008). Calcium-modulating cyclophilin ligand regulates membrane trafficking of postsynaptic GABA(A) receptors. Molecular and Cellular Neuroscience. 38(2):277-289.

25.

Deng, L.*, Fang, C., Dong, N., Luscher, B., Chen G. Sequential postsynaptic maturation governs the temporal order of GABAergic and glutamatergic synaptogenesis in rat embryonic cultures. Journal of Neuroscience. 2007 Oct 3;27(40):10860-9. (*Equal contribution)

26.

Yao,J., Qi, J. S., and Chen, G. Actin-dependent activation of presynaptic silent synapses contributes to long-term synaptic plasticity in developing hippocampal neurons. Journal of Neuroscience. 2006 Aug 2;26(31):8137-47.

27.

Qi, J., Yao, J., Fang, C., Luscher, B., and Chen G (2006). Downregulation of Tonic GABA Currents Following Epileptogenic Stimulation of Rat Hippocampal Cultures. Journal of Physiology. 577(2): 579-590.